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Clinical Trials/NCT01895686
NCT01895686CompletedNot Applicable

Comparison of Visante and Cirrus Optical Coherent Tomography for Assessment of the Anterior Segment

Wills Eye1 site in 1 country54 target enrollmentStarted: November 2011Last updated:
Conditions

Trial Snapshot

Phase
Not Applicable
Status
Completed
Sponsor
Enrollment
54
Locations
1
Primary Endpoint
anterior angle measurement

Study Overview

Brief Summary

The aim of this study is to analyze similarities and evaluate interchangeability of Visante and Cirrus OCT (optical coherent tomography)and to compare agreement between gonioscopy and the two systems for evaluation of anterior segment parameters.

Detailed Description

All participants underwent routine ophthalmic examination by their physician. Three independent examiners performed gonioscopy using Spaeth Gonioscopic Grading System. Findings were recorded independently along with risk assessment of angle being closed as: high, medium, and low or no risk. Patient information was not available to doctor during gonioscopy. One eye of each patient was imaged using both Visante and Cirrus OCT. Imaging was performed under scotopic and photopic conditions and obtained from horizontal (3:00 and 9:00 o'clock) and vertical (6:00 and 12:00 o'clock) meridians. The same experienced independent examiner performed all Cirrus measurements. Visante was performed by 3 trained technicians using same protocol.

OCT images were exported and masked to be evaluated for presence of open or closed anterior chamber angle. Masked images were presented with no other patient information available to two examiners with glaucoma training working together to score on basis of iridocorneal angle as, closed (0 degree), high possibility (10 degree), medium risk (20 degree), and low or no risk (> 30 degree).

Study Design

Study Type
Observational
Observational Model
Cohort
Time Perspective
Prospective

Eligibility Criteria

Ages
18 Years to — (Adult, Older Adult)
Sex
All
Accepts Healthy Volunteers
No

Inclusion Criteria

  • 18 years of age and older with open angle, narrow angle and angle closure

Exclusion Criteria

  • All lasers or intraocular surgery (cataract, glaucoma, retina, cornea)

Outcomes

Primary Outcomes

anterior angle measurement

Time Frame: 1 day

comparison of AS assessment by Cirrus, Visante, gonioscopies

Secondary Outcomes

No secondary outcomes reported

Investigators

Sponsor
Wills Eye
Sponsor Class
Other
Responsible Party
Principal Investigator
Principal Investigator

L. Jay Katz MD

Principal Investigator

Wills Eye

Study Sites (1)

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