PACTR202007465309582已完成3 期
Effect of concurent training (strength and endurance) on biochemical and neurophysiological adaptations and physical and psycho-cognitive performance in people with multiple sclerosis: role of melatonin or synbiotics supplementation
The Research Unit of the assessment of musculoskeletal disorders0 个研究点目标入组 60 人开始时间: 2020年6月3日最近更新:
试验速览
- 阶段
- 3 期
- 状态
- 已完成
- 发起方
- 入组人数
- 60
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 19 Year(s) 至 44 Year(s)（—）
- 性别
- All
入选标准
- •*Patients under 60 years old
- •*Sedentary.
- •*EDSS : from 0 to 5
- •*Body mass index (BMI) <30 (kg/m²)
排除标准
- •* 3 months before the study: Taking another supplement, antioxidant substances, vitamins or anti-inflammatory drugs.
- •* No hormonal treatments or sleeping pills (hypnotics and anxiolytics) two weeks before the study * Patients who have undergone a rehabilitation protocol in the previous 6 months
- •*A contraindication or an allergy to melatonin or probiotics
- •* Smoking, alcoholism, drugs * Other chronic or autoimmune neurodegenerative comorbidities. * Diabetes, osteoporosis, other neurological, vestibular, cognitive, orthopedic, visual and psychiatric disorders.
- •*Any contraindication to the practice of a physical activity (serious cardiovascular or pulmonary diseases, an exacerbation of the MS in the 4 weeks preceding the tests)
- •*EDSS> or = 6 (Dependent patients or use assistive devices) * Pregnant or lactating women in the last six months,
- •*Patients with nephrolithiasis in the last 5 years (related to synbiotic) * Women with irregular menstruation and unwilling to use appropriate contraception
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