Mechanical Ventilation Weaning Prediction Improved by Diaphragmatic Ultrasound Associated With the Rapid Shallow Breathing Index
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- Difference between the RSBI area and the RSDI AUC
研究概览
简要总结
The Rapid Shallow Breathing Index (RSBI) is the ratio between respiratory rate (RR) and tidal volume (VT). It is routinely used to predict mechanical ventilation weaning outcome in ICU patients. However RSBI doesn't reflect the muscular contribution of diaphragm or accessory muscles in generating tidal volume. Actually, diaphragmatic dysfunction can even delay weaning process, because accessory muscles are more fatigable than the diaphragm.
Hence, the investigators hypothesized that diaphragmatic displacement (DD) could be associated with RSBI in a new index named Rapid Shallow Diaphragmatic Index (RSDI) such as: RSDI = RSBI/DD.
The aim of this study is to compare the ability of the RSDI versus the traditional RSBI to predict weaning success in ready-to-wean patients.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age ≥ 18 years
- •Mechanically ventilated patient > 24 hours
- •Weaning ventilator phase (PEEP < 9 cmH2O and Support < 15 cm H2O)
- •Ventilated via tracheostomy tube patient can be included on removal day of the cannula
- •Patient's agreement to participate
排除标准
- •Moribund patient
- •Decision to forgo life sustaining therapy patient
- •Patient with ventilation via tracheostomy tube before admission to ICU
- •BMI > 45
研究组 & 干预措施
Ventilated patients
During a spontaneous breathing trial (SBT) we will simultaneously, for all included patient, assess diaphragmatic displacement (DD) using ultrasonography, respiratory rate (RR) and tidal volume (VT) on ventilator screen.
干预措施: assess diaphragmatic displacement (DD) using ultrasonography (Diagnostic Test)
结局指标
主要结局
Difference between the RSBI area and the RSDI AUC
时间窗: 72 hours post-extubation
Difference between the RSBI area under the receiving operator character curve (AUC) and the RSDI AUC in predicting success of mechanical ventilation weaning.
次要结局
- Find reasons for non-extubation when criteria are gathered(72 hours post-extubation)
- Estimate average duration of mechanical ventilation in central nervous system disorder patient(72 hours post-extubation)
- Compare traditional RSBI values recorded with scientific publications(72 hours post-extubation)
- Find a cut-off value for RSDI(72 hours post-extubation)