ISRCTN12205188已完成未知
Prospective randomised controlled trial to investigate the effectiveness of inhalers for the relief of breathlessness in patients with lung cancer and chronic obstructive pulmonary disease (COPD)
The Royal Marsden NHS Foundation Trust (UK)0 个研究点目标入组 72 人开始时间: 2011年2月28日最近更新:
适应症
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 发起方
- 入组人数
- 72
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 性别
- All
入选标准
- •1. Male or female, age > 35 years
- •2. Diagnosis of non-small cell lung cancer (NSCLC), small cell lung cancer (SCLC) or mesothelioma
- •3. Diagnosis of COPD
- •4. Subjective dyspnoea of visual analogue score (VAS) = 4
排除标准
- •1. Involvement in any other studies of breathlessness
- •2. Reversible causes of breathlessness
- •3. Patients receiving radiotherapy, chemotherapy, biological therapy or surgery. Or a plan to commence these treatments within 4 weeks
- •4. Current use of bronchodilators either inhaled or oral (aminophyline, methyxanthines) except for short-acting bronchodilators
- •5. Recent change to oral corticosteroid therapy dose (within 1 week of randomisation)
- •6. Current use of beta-blockers for any reason
- •7. Current use of anti-cholinergic containing drugs
- •8. Current use of potent CYP30 inhibitors (ritonavir, ketoconazole, itraconazole)
- •9. Patients with the following conditions:
- •9.1. Asthma
- •9.2. Severe cardiovascular disorders (myocardial infarction within 6 week)
- •9.3. Heart rhythm abnormalities
- •9.4. Thyrotoxicosis
- •9.5. Uncorrected hypokalaemia
- •9.6. Glaucoma
- •9.7. Prostate problems
- •9.8. Patients with difficulty passing urine
- •9.9. Renal failure
- •9.10. TB (current or previous)
- •10. Pregnancy
- •11. Patients with hypersensitivity to any of the study drugs, lactose allergy
研究者
相似试验
进行中（未招募）
1 期
Prospective randomised controlled trial to investigate the effectiveness of inhalers for the relief of breathlessness in patients with lung cancer and COPD - Airway disease optimisation of pharmaco-therapy in lung cancerChronic obstructive pulmonary disease, lung cancerEUCTR2010-021412-42-GBRoyal Marsden Hospital65
招募中
2 期
Effect of yokukansan in the perioperative periodbreast cancerJPRN-jRCT1031190049Baba Hiroshi40
进行中（未招募）
不适用
A long term trial to investigate the effects on strength of the foot and leg, between a mobile shoe and a standard school shoe in children aged nine to twelve.ACTRN12618001096246The University of Sydney35
已完成
不适用
Prospective randomized controlled study to investigate the effect of Yokukansan on perioperative anxiety and pain.breast cancer patientsJPRN-UMIN000028998iigata university Guraduate school of medical and dental sciences80
已完成
不适用
A prospective randomised controlled trial into the role of hydrotherapy and physiotherapy in reducing the incapacity during acute phase of Legg-Calve-Perthes diseaseMusculoskeletal Diseases: Legg-Perthes diseaseMusculoskeletal DiseasesJuvenile osteochondrosis of head of femur (Legg-Calve-Perthes)ISRCTN45181565Record provided by the NHS Trusts Clinical Trials Register - Department of Health (UK)