ISRCTN12205188
Completed
未知
Prospective randomised controlled trial to investigate the effectiveness of inhalers for the relief of breathlessness in patients with lung cancer and chronic obstructive pulmonary disease (COPD)
The Royal Marsden NHS Foundation Trust (UK)0 sites72 target enrollmentFebruary 28, 2011
Overview
- Phase
- 未知
- Intervention
- Not specified
- Conditions
- ung cancer, Chronic obstructive pulmonary disease (COPD)
- Sponsor
- The Royal Marsden NHS Foundation Trust (UK)
- Enrollment
- 72
- Status
- Completed
- Last Updated
- 7 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •1\. Male or female, age \> 35 years
- •2\. Diagnosis of non\-small cell lung cancer (NSCLC), small cell lung cancer (SCLC) or mesothelioma
- •3\. Diagnosis of COPD
- •4\. Subjective dyspnoea of visual analogue score (VAS) \= 4
Exclusion Criteria
- •1\. Involvement in any other studies of breathlessness
- •2\. Reversible causes of breathlessness
- •3\. Patients receiving radiotherapy, chemotherapy, biological therapy or surgery. Or a plan to commence these treatments within 4 weeks
- •4\. Current use of bronchodilators either inhaled or oral (aminophyline, methyxanthines) except for short\-acting bronchodilators
- •5\. Recent change to oral corticosteroid therapy dose (within 1 week of randomisation)
- •6\. Current use of beta\-blockers for any reason
- •7\. Current use of anti\-cholinergic containing drugs
- •8\. Current use of potent CYP30 inhibitors (ritonavir, ketoconazole, itraconazole)
- •9\. Patients with the following conditions:
- •9\.1\. Asthma
Outcomes
Primary Outcomes
Not specified
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