Pertubation with Lignocaine in Endometriosis Associated Symptoms Effect study (PLEASE) - PLEASE

Karolinska Institute, Danderyds hospital0 个研究点开始时间: 2006年9月19日最近更新: 2012年3月19日

试验速览

暂无简介。

•Women 20-40 years,
•Endometriosis verified by laparoscopy,
•Dysmenorrhea or pelvic pain, , defined as having a pain-score of >5 at the visual analogue scale(VAS),
•Normal Fallopian tubes,
•Regular menstruation bleeding (If not on hormonal treatment she should have been without combined contraceptive pills or gestagens for 1 month or without GnRH-agonists for at least 6 months, Treatment with oral contraceptives should have been ongoing for at least 1 month and shall continue during the trial),
•No wish for pregnancy at present,
•Normal Pap-smear,
•Negative Chlamydia-test
•Negative pregnancy-test.
•Informed consent given and signed
•Are the trial subjects under 18? no
•Number of subjects for this age range:
•F.1.2 Adults (18-64 years) yes
•F.1.2.1 Number of subjects for this age range
•F.1.3 Elderly (>=65 years) no
•F.1.3.1 Number of subjects for this age range

•Exclusion criterias:
•Continous treatment with NSAID, corticosteroids or other medicine that may increase risk for infection,
•Clinical signs of pelvic inflammatory disease,
•Known hyperreactivity to local anesthesia,
•Fibriods>2cm,
•Ongoing treatment with GnRH-analog,
•Ongoing continous treatment with gestagens,
•Pregnancy or wish for pregnancy the forthcoming year,
•Pelvic adhesions,
•Verified occluded or reduced patency in the Fallopian tubes,
•Inability to understand information or comply with the study procedures
•Participation in a clinical study within one year before the present study.
•Any disease or laboratory finding considered of importance by the investigator not to include the patient.

发起方

Karolinska Institute, Danderyds hospital