Association Between a Peri-traumatic Dissociation State and the Occurrence of Post-traumatic Stress Syndrome

Not Applicable

Completed

• Conditions: Severe Trauma; General Anaesthesia
• Interventions: Diagnostic Test: PDEQ, PCL-5 and demographic survey

• Registration Number: NCT03930966
• Lead Sponsor: University Hospital, Brest

Brief Summary

Patients will be selected after studying clinical records.Patients who had general anesthesia due to an injury related to severe trauma within 6 to 12 months prior to inclusion will be included.

Three self-survey will be completed by the patient: PDEQ, PCL-5 and a demographic questionnaire. According to the PDEQ and PCL-5 scores, an association between a peri-traumatic dissociation state and a post-traumatic stress disorder can be established.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2019-02-28
• Study Start: 2019-04-09
• Study First Submitted QC: 2019-04-25
• Study First Posted: 2019-04-29
• Status Verified: 2021-09
• Primary Completion: 2021-12-15
• Study Completion: 2021-12-15
• Last Update Submitted: 2022-01-04
• Last Update Posted: 2022-01-05

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 148

Inclusion Criteria

• Patients with general anesthesia for a surgical wound with violent trauma in the road, a fall of more than 6 meters, burn, accident at work, explosion, aggression) in the 6 to 12 months before the inclusion
• Time between trauma and general anesthesia should not exceed 48 hours
• Patient agreeing to participate in the study.

Exclusion Criteria

• Minor patients
• Patients under curatorship, and tutorship
• Patient deprived of liberty
• Patients who do not speak French
• Patients who are not in satisfactory neurological state to answer the questionnaire (pyschotic, demented states)
• Patients who have been sedated (apart from general anesthesia) when receiving or having a Glasgow score <14

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
PDEQ, PCL-5 and demographic survey	PDEQ, PCL-5 and demographic survey	State of the patient evaluated with questionnaires to make the connection between peri-traumatic dissociation and the occurrence of post-traumatic stress disorder

Primary Outcome Measures

Name	Time	Method
Studying association between the presence of peri-traumatic dissociation state and the achievement of post-traumatic stress disorder between 6 and 12 months in traumatized patients	study baseline (6 to 12 months after initial hospitalisation)	Association will be measured using PDEQ scale and PCL-5 scale. The peri-traumatic dissociation will be evaluated by the Peri-traumatique Dissociation Experience Questionnary (PDEQ scale). This questionnaire contains ten items to study the presence or not of a peri-traumatic dissociation state. The items are scored on a 5-point Likert scale ranging from 1 (not at all true) to 5 (extremely true). The total score is the sum of all the items. A score from 15 indicates a significant dissociation.; The presence or not of a Post-Traumatic Stress Disorder (PTSD) will be evaluated by the Post-Traumatic Stress Disorder Checklist Scale-Version DSM 5 (PCL-5). This questionnaire contains twenty items to study the presence or not of a PTSD. A total score for symptom severity (0-80) can be obtained by summing the scores for each of the 20 items. A score over 31 indicates a PTSD.

Secondary Outcome Measures

Name	Time	Method
Measurement of the frequency of PTSD after severe trauma requiring general anesthesia.	study baseline (6 to 12 months after initial hospitalisation)
Research of Risk Factors Associated with the Occurrence of PTSD	study baseline (6 to 12 months after initial hospitalisation)

Trial Locations

Locations (1)

CHRU Brest; 🇫🇷 Brest, France