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Clinical Trials/NCT02371733
NCT02371733
Completed
Not Applicable

Effects of Upper Extremity Aerobic Exercise Training on Functional Exercise Capacity in Patients With Pulmonary Arterial Hypertension

Gazi University1 site in 1 country30 target enrollmentApril 2015

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Pulmonary Arterial Hypertension
Sponsor
Gazi University
Enrollment
30
Locations
1
Primary Endpoint
Functional exercise capacity (Oxygen consumption measurement during test)
Status
Completed
Last Updated
7 years ago

Overview

Brief Summary

Decreased exercise capacity, peripheral muscle strength and quality of life and increased dyspnea and fatigue perception is prevalent in patients with pulmonary arterial hypertension. It was demonstrated exercise training has beneficial effects in patients with pulmonary arterial hypertension. However, no study investigated the effects of upper extremity aerobic exercise training, therefore effects of upper extremity aerobic exercise training on outcomes in patients with pulmonary arterial hypertension.

Detailed Description

Patients were diagnosed with pulmonary arterial hypertension according to the Task Force for the Diagnosis and Treatment of Pulmonary Hypertension of f the European Society of Cardiology (ESC) and European Respiratory Society (ERS). Primary outcome measurement was exercise capacity, secondary outcomes were respiratory and peripheral muscle strength, physical activity, quality of life, fatigue, dyspnea and depression.

Registry
clinicaltrials.gov
Start Date
April 2015
End Date
April 2018
Last Updated
7 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Meral Boşnak Güçlü

Assoc. Prof

Gazi University

Eligibility Criteria

Inclusion Criteria

  • Clinically stable
  • Under standard medication
  • Group 1 pulmonary arterial hypertension patients
  • Having no exacerbation or infection

Exclusion Criteria

  • Cognitive disorders
  • Orthopedic and neurological problems
  • Pneumonia or acute infection
  • Stage 4 heart failure
  • Having no comorbidity to avoid performing evaluation and training

Outcomes

Primary Outcomes

Functional exercise capacity (Oxygen consumption measurement during test)

Time Frame: 6 weeks

Six minute walk test (6MWT)

Secondary Outcomes

  • Generic quality of life(6 weeks)
  • Maximum inspiratory and expiratory muscle strength (MIP, MEP)(6 weeks)
  • Peripheral muscle strength(6 weeks)
  • Pulmonary functions(6 week)
  • Physical activity(6 weeks)
  • Dyspnea(6 weeks)
  • Fatigue(6 weeks)
  • Depression(6 weeks)

Study Sites (1)

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