Effects of Upper Extremity Aerobic Exercise Training on Functional Exercise Capacity in Patients With Pulmonary Arterial Hypertension
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Sponsor
- Gazi University
- Enrollment
- 30
- Locations
- 1
- Primary Endpoint
- Functional exercise capacity (Oxygen consumption measurement during test)
Study Overview
Brief Summary
Decreased exercise capacity, peripheral muscle strength and quality of life and increased dyspnea and fatigue perception is prevalent in patients with pulmonary arterial hypertension. It was demonstrated exercise training has beneficial effects in patients with pulmonary arterial hypertension. However, no study investigated the effects of upper extremity aerobic exercise training, therefore effects of upper extremity aerobic exercise training on outcomes in patients with pulmonary arterial hypertension.
Detailed Description
Patients were diagnosed with pulmonary arterial hypertension according to the Task Force for the Diagnosis and Treatment of Pulmonary Hypertension of f the European Society of Cardiology (ESC) and European Respiratory Society (ERS). Primary outcome measurement was exercise capacity, secondary outcomes were respiratory and peripheral muscle strength, physical activity, quality of life, fatigue, dyspnea and depression.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Parallel
- Primary Purpose
- Supportive Care
- Masking
- Triple (Participant, Investigator, Outcomes Assessor)
Eligibility Criteria
- Ages
- 18 Years to 65 Years (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •Clinically stable
- •Under standard medication
- •Group 1 pulmonary arterial hypertension patients
- •Having no exacerbation or infection
Exclusion Criteria
- •Cognitive disorders
- •Orthopedic and neurological problems
- •Pneumonia or acute infection
- •Stage 4 heart failure
- •Having no comorbidity to avoid performing evaluation and training
Arms & Interventions
Training Group
Intervention:Training group will receive upper extremity aerobic exercise training using arm ergometer and breathing exercises.
Intervention: Upper extremity aerobic exercise training (Other)
Control Group
Sham: Control group will receive alternative upper extremity exercises and breathing exercises.
Intervention: Alternative upper extremity exercises (Other)
Outcomes
Primary Outcomes
Functional exercise capacity (Oxygen consumption measurement during test)
Time Frame: 6 weeks
Six minute walk test (6MWT)
Secondary Outcomes
- Depression(6 weeks)
- Fatigue(6 weeks)
- Generic quality of life(6 weeks)
- Maximum inspiratory and expiratory muscle strength (MIP, MEP)(6 weeks)
- Physical activity(6 weeks)
- Dyspnea(6 weeks)
- Peripheral muscle strength(6 weeks)
- Pulmonary functions(6 week)
Investigators
Meral Boşnak Güçlü
Assoc. Prof
Gazi University