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Clinical Trials/NCT07446127
NCT07446127
Recruiting
Not Applicable

Evaluation of the Effect of Adjunctive Diode Laser Therapy in Mechanical Scaling and Root Surface Debridement in Non-Surgical Periodontal Therapy

Tel Aviv University1 site in 1 country20 target enrollmentStarted: January 1, 2026Last updated:

Overview

Phase
Not Applicable
Status
Recruiting
Enrollment
20
Locations
1
Primary Endpoint
PPD

Overview

Brief Summary

The goal of this clinical trial is to evaluate the efficacy of adjunctive application of diode laser to mechanical, non-surgical root surface debridement in patients attending periodontal office. The main question it aims to answer is:

To compare the clinical effectiveness of adjunctive application of a 940-nm diode laser with root surface debridement to the effectiveness of root surface debridement alone.

This study is a split-mouth design, where each quadrant will be randomly allocated to one of the following groups:

Control group (root surface debridement - RsD): scaling and root planing alone. Laser group (RsD + laser): scaling and root planing with adjunctive diode laser therapy Quadrants will be randomly allocated to the treatment groups

Study Design

Study Type
Interventional
Allocation
Randomized
Intervention Model
Single Group
Primary Purpose
Treatment
Masking
None

Eligibility Criteria

Ages
18 Years to — (Adult, Older Adult)
Sex
All
Accepts Healthy Volunteers
No

Inclusion Criteria

  • Systemically healthy patients
  • Each patient should have more than 20 teeth remaining, and at least 5 teeth per quadrant
  • Each patient presented ≥ 30% of sites involved
  • At least 2 teeth with a probing depth of ≥ 5 mm in each quadrant, with evident radiographic bone loss.

Exclusion Criteria

  • History of systemic diseases affecting the periodontium
  • Smokers and alcoholic patients
  • Use of medication within the last 6 months, which might affect the periodontal status
  • Pregnant and lactating women
  • Patients who had any periodontal treatment ≤ 12 months before the examination.

Arms & Interventions

test quadrants

Experimental

two contralateral jaw quadrants in each patient mouth will undergo RsD and Laser Diode assisted SRP treatment

Intervention: LASER assisted SRP (Device)

control quadrants

Active Comparator

two contralateral jaw quadrants in each patient mouth (same patient cohort) will undergo RsD treatment only

Intervention: RsD (Device)

Outcomes

Primary Outcomes

PPD

Time Frame: prior to treatment and 12 weeks and 6 months after treatment

periodontal pocket depth

Secondary Outcomes

  • CAL(prior to treatment and 12 weeks and 6 months after the treatment)
  • BOP(prior to treatment and 12 weeks and 6 months after the treatment)

Investigators

Sponsor Class
Other
Responsible Party
Principal Investigator
Principal Investigator

Michael Saminsky

Doctor

Tel Aviv University

Study Sites (1)

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