The Influence of the Nutritional Status of Women Between 30 and 45 Years of Age on the Condition of the Skin and Body Composition

Completed

• Conditions: Skin Condition; Body Composition
• Interventions: Other: dietary habit

• Registration Number: NCT05712590
• Lead Sponsor: VIST - Faculty of Applied Sciences

Brief Summary

Goal is to investigate the differences in skin condition and body composition among women with different dietary habits aged 30-45 years. Study will be focused onto sub-groups of female subjects following omnivorous, vegetarian or vegan diet.

Detailed Description

Investigators will investigate differences among female subjects aged 30-45 years following one of the following diet for at least 3 years:

* vegan

* vegetarian

* omnivorous

Study will focus into the differences in dermal protein density and dermal thickness, skin hydration and trans-epidermal water loss. Study will focus also into body composition, specifically into % of body fat and % of lean body weight.

Study Timeline

• Study First Submitted: 2022-12-07
• Study Start: 2022-12-19
• Study First Submitted QC: 2023-01-31
• Study First Posted: 2023-02-03
• Status Verified: 2023-04
• Primary Completion: 2023-05-10
• Study Completion: 2023-08-31
• Last Update Submitted: 2024-01-05
• Last Update Posted: 2024-01-08

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 48

Inclusion Criteria

• women
• aged 30-45 years
• vegan or vegetarian or omnivorous diet for at least 3 years,
• body mass index (BMI) between 18.5 and 25.

Exclusion Criteria

• smoking or have smoked in the past (quit less than 3 years ago),
• pregnancy or breastfeeding,
• pre-menopause
• medications that increase skin dryness (e.g. retinoids),
• visiting solariums,
• visiting of the fitness center more than 3 times a week,
• regular consumption of protein supplements (including food supplements with collagen),
• chronic and acute skin diseases,
• chronic and acute diseases of the gastrointestinal tract (e.g. celiac disease),
• lactose intolerance,
• various diets (e.g. health, slimming),
• damaged skin in the test area (inner forearm),
• hyperhidrosis or increased sweating,
• diseases that cause a chronically damaged skin barrier (e.g. atopic dermatitis, ichthyosis),
• cancer diseases,
• pacemaker.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Vegetarians	dietary habit	In this group women aged 30-45 years that follow vegetarian (lacto-ovo/lacto/ovo) diet for at least 3 years will be included.
Vegans	dietary habit	In this group women aged 30-45 years that follow vegan diet for at least 3 years will be included.
Omnivores	dietary habit	In this group women aged 30-45 years that follow omnivorous diet for at least 3 years will be included.

Primary Outcome Measures

Name	Time	Method
Trans epidermal water loss	baseline	It will be measured on forearm using Cortex DermaLab open-chamberTEWL probe.
Dermal density	baseline	It will be measured on forearm using ultrasonography as score 0-100.
Dermal thickness	baseline	It will be measured on forearm using ultrasonography in micrometeres.
% of lean body weight	baseline	It will be measured using Multiscan is a spectroscopy (BIS).
Skin hydration	baseline	It will be measured on forearm using Cortex DermaLab flat hydration probe in microsiemens.
Skin elasticity	baseline	It will be measured on forearm using Cortex DermaLab elasticity probe in MPa.
% of body fat	baseline	It will be measured using Multiscan is a spectroscopy (BIS).

Trial Locations

Locations (1)

VIST - Faculty of applied sciences, Institute of Cosmetics; 🇸🇮 Ljubljana, Slovenia