Comparison of Nirgundi Churna & Trikatu Churna in Obesity

Recruiting

Conditions: Obesity, unspecified. Ayurveda Condition: MEDOROGAH,

Registration Number: CTRI/2023/04/051738

Lead Sponsor: Dr Vishal Agarwal

Brief Summary: Obesity is a leading preventable cause for death worldwide with increasing rates in adults and children. Globally more than 7 billion people are overweight. In 2015, 600 million adults and100 million children were obese in 195 countries. Authorities view it as one of the most serious public health problems in 21st century.Obesity is regarded as Medoroga a disorder of Medodhathu-adiopse tissue and fat metabolism. There are health issues associated like cardiovascular diseases, type 2 diabetes, musculoskeletal disorders, cancer of endometrium, cervix and colon, infertility, gallstones. Overweight refers to an excessive amount of body weight that includes muscles, bone, fat and water or when a person weighs more than what is considered to be healthy for his age and height.Medoroga is classified under Santharpanajanya Vyadhi and Sthoulya as a KaphajaNanatmaja vyadhi.Acharya Charaka and Vagbhata have mentioned â€œkarshyamevavaramsthoulyamna hi sthoolasyabheshajamâ€ implying Atisthulas are more liable to beat health risk than Atikrusha. Sthoulya is primarily Santharpanajanya Vyadhi so Chikitsa aims towards Apatarpanaupakramai.e; Langhana, Pachana, Deepana and Shodhana.Sthoulya has bad prognosis if not duly managed as it can cause death due to its many fold complications.Nidana Sevana leads to impaired Dhatwagni thus causing accumulation of Medas in excess and which later leads to Sthoulya.The treatment of Obesity in an initial stage, correction of Agni has itsimportance. Vata and Kapha being the main components of vitiation in Medoroga, AgniSandhookshana is primarily focused. The main treatment for Obesity cannot be dieting andexercise. Diet program may produce weight loss in short term, but maintaining the weight loss isfrequently difficult and often require making exercise and a low calory diet as a permanent part of a personâ€™s lifestyle and the success rates ranges from 2 to 20%. The medicines used in Obesity (Rimonabant, sibutramine, orlistat) affects long term and complication of these are very common. Its uses are associated with high rates of Gastro Enteric side effects4,5. So it is better to adopt safe and effective treatment measures to prevent Obesity and Overweight by applying principles of Ayurveda.Keeping all the points of samprapti a sincere attempt has been made to check all the pathological factors in Medoroga. Considering the above points the clinical trial will be aimed to come outwith the help of effective formulations i.e; nirgundi churna(ref kaidev nighantu) composition nirgundi patra churna and trikatu churna (ref sharangdhar samhita) composition sunthi 1 pat pippali 1 pat and marich 1 part.

a comparative study of nirgundi churna and trikatu churna in the management of sthaulya w.s.r to obesity.

Detailed Description: Not available

Recruitment & Eligibility

Status: Open to Recruitment

Sex: All

Target Recruitment: 100

Inclusion Criteria

Patient at least fulfilling 2 of following 3 criteria 1.
Subject with bmi more than 25 to 40.
Sthaulya diagnosed according to sign & symptoms as per classical text.
Sthaulya patient without any systemic disorder.

Exclusion Criteria

Patient at least fulfilling 3 of following 5 criteria 1.
History of any systemic illness.
Obesity caused by hormonal imbalance 3.
Any kind of skin disease depends on steroidal drugs.
Pregnant and lactacting mother.
Age less than 18 years and more than 50 years.

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
3.Reduction in hip waist ratio	90 days
objective parametes like	90 days
3 nidraadhikya	90 days
Subjective parameters like	90 days
1.aalasya	90 days
2.alpabala	90 days
1.BMI	90 days
2.Weight	90 days

Secondary Outcome Measures

Name	Time	Method
Reduction in the objective criteria :	â€¢ Weight and BMI reduction

Trial Locations

Locations (1): Rohilkhanda ayurvedic medical college and hospital bareilly
🇮🇳
Bareilly, UTTAR PRADESH, India
Rohilkhanda ayurvedic medical college and hospital bareilly
🇮🇳Bareilly, UTTAR PRADESH, India
Dr Rakesh Kumar Tewari
Principal investigator
8755922339
ramchdean@gmail.com