A Pilot Two-arm, Individual-level, Randomised Controlled Trial to Assess the Effect of an Intervention Integrating Contingency Management (Financial Incentives) to Enhance Hepatitis C Treatment Uptake Following Dried Blood Spot Hepatitis C RNA Testing Among People With Recent Injecting Drug Use Attending Needle and Syringe Programs
试验速览
- 阶段
- 不适用
- 入组人数
- 400
- 主要终点
- The proportion of participants who initiate Hepatitis C Virus treatment within 12 weeks of testing
研究概览
简要总结
A pilot two-arm, individual-level, randomised controlled trial to assess the effect of an intervention integrating contingency management (financial incentives) to enhance hepatitis C treatment uptake following dried blood spot hepatitis C RNA testing among people with recent injecting drug use attending needle and syringe programs: the AMPLIFY study
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Other
- 盲法
- Single (Investigator)
盲法说明
Participants will be randomised with a computerised random number generator (or random number table) with block randomisation to assist with keeping participant balance between study arms with a small sample size.
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Participants have voluntarily signed the informed consent form
- •18 years of age or older
- •Recent injecting drug use (previous six months)
排除标准
- •Inability or unwillingness to provide informed consent
结局指标
主要结局
The proportion of participants who initiate Hepatitis C Virus treatment within 12 weeks of testing
时间窗: 6 months
Data will be presented in percentages and mean (SD) or median values (interquartile range), as appropriate. Chi square test or Fisher's exact test will be utilised, as appropriate, to examine between group differences.
次要结局
- Feasibility of recruitment through a peer-based referral incentivization scheme(6 months)
- Time to HCV treatment initiation(6 months)
- Participant perceptions and acceptability of being involved in a contingency management study will be assessed by study questionnaire(6 months)
- Feasibility of a contingency management intervention to enhance hepatitis C treatment uptake(6 months)
- Time to HCV treatment completion(6 months)
- Time to visit to confirm viral cure (e.g. sustained virological response, SVR12)(6 months)