Collection of Biological and Environmental Samples and Clinical Data From Anonymous Adult Men and Women for Quality Control and Methods Development and Evaluation (ASCA)

Background:

Scientists want to improve new studies on how the environment, diet, and genetic factors affect human health. To do this, they need biological samples and clinical data. They want to find better ways to collect, handle, store, and test these samples and data. This could make them more useful for research.

Objective:

To collect anonymous samples and clinical data from people. To find better ways to collect, handle, store, and test them to support health research.

Eligibility:

Healthy people ages 18 and older

Design:

Participants will complete a screening form by phone or in person. The form could include questions about age, race, ethnicity, menopause status, or pregnancy.

Participants will donate a specific amount of a sample. This could be blood, breast milk, cerumen, ear wax, exhaled breath, hair, mucosal or skin cells, nail clippings, saliva, semen, stool, or urine.

Participants may provide an environmental sample such as dust, water, soil, air, or plant life.

Participants may get kits to collect their samples. They may also donate them at a clinic visit.

Visit will take about 30 minutes. They may include:

Sample collection

Questions about diet, smoking, alcohol use, medication, menstrual cycle, and health

Measurement of body composition, naturally occurring radioactivity, or Doppler blood flow

Moderate exercise

Flexibility, muscle strength, or sensory testing

Participants may be asked to participate several times during the study.