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CIMAvax-EGF®-post-COVID19 convalescent with respiratory disorders-adults-Phase II (CORVAXCIM)

Phase 2
Not yet recruiting
Conditions
Respiratory disorders in convalescent patients from SARS-CoV-2 infection
COVID-19
SARS-CoV2
Coronavirus Infections
SARS Virus
Coronaviridae Infections
Betacoronavirus
Pulmonary Fibrosis
Lung Diseases
Respiratory Tract Diseases
Registration Number
RPCEC00000375
Lead Sponsor
Center of Molecular Immunology (CIM)
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Pending
Sex
All
Target Recruitment
135
Inclusion Criteria

1. Willingness of the patient by signing the informed consent.
2. Subject of any sex and age greater than or equal to 18 years.
3. Subjects for whom at least 14 days have elapsed from discharge from the post-COVID-19 patient care service or referral of the specialized consultation.
4. Patients with respiratory clinical manifestations and deterioration of respiratory function due to spirometric or radiological functional pattern.
5. Subject that in the pre-inclusion checkup they have: hemoglobin = 9 g/L, leukocytes = 3.4x109 L, absolute neutrophil count = 1.5 x 109 L.
6. Liver and kidney function tests in normal ranges.

Exclusion Criteria

1. Patients with pre-existing lung disorders (including pulmonary fibrosis, COPD, severe asthma, lung cancer, etc).
2. Patients with confirmed severe or life-limiting chronic disease, or a history of angioedema prior to COVID-19 infection.
3. Pregnancy or lactation period.
4. Subjects of childbearing age who are not using an adequate method of contraception prior to their inclusion in the study.
5. Subject that they are receiving another product under investigation.
6. Known hypersensitivity to any of the components of the formulation under study.
7. Obvious mental incapacity to issue consent and act accordingly with the study.

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod

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