Cluster Headache and SPINK-1 Gene
Not Applicable
Completed
- Conditions
- Episodic or Chronic Cluster Headache
- Interventions
- Genetic: blood sample
- Registration Number
- NCT02585739
- Lead Sponsor
- Assistance Publique Hopitaux De Marseille
- Brief Summary
Cluster headache (CH) is a rare, excruciating primary headache disorder. A genetic basis has been suggested by family and twin studies, but the mode of transmission seems to vary and the amount of heritability is unclear.
The number of genetic association studies investigating variants implicated in the pathophysiology of CH is limited. The HCRTR2 1246G \> A and the ADH4 925A \> G polymorphisms have been associated with CH. The former has been confirmed and may affect the hypothalamic hypocretin system. The aim of the present study was to investigate the possible link between SPINK 1 gene and cluster headache.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 42
Inclusion Criteria
- People aged 18 or over
- Patient consulting in Marseille's or Nice's Pain departments
- Patient agreeing to participate to the research study
- Patient with health insurance
Exclusion Criteria
- People aged under 18
- Patient refusing to participate to the research study
- Patient with deprivation of liberty
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description patient blood sample patient with Cluster headache healthy subject blood sample patient without Cluster headache
- Primary Outcome Measures
Name Time Method SPINK1 genotyping 2 months
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
APHM
🇫🇷Marseille, France