Study of Aragvadhadi gana ghanvati (tablet) and panchkarma (mainly virechan karma) in skin disorder patients (Psoriasis)

Phase 2

Not yet recruiting

Conditions: Psoriasis, unspecified,

Registration Number: CTRI/2020/03/024090

Lead Sponsor: Department of Kayachikitsa Shri Narayan Prasad Awasthi Govt Ayurved College Raipur CG

Brief Summary: Ayurved is an ancient medical science. It is notonly medical system but also it includes life philosophy in which there isdescription of seasonal regimen such as Dincharya, Ratricharya and Ritucharya.A person who follows this seasonal regimen described in Ayurved Samhitaâ€™s isalways healthy. Intake of Mithya Ahara Vihara causes suffering from variousdiseases. In Ayurved classics, there is complete description of how to regainhealth. Two main aims of Ayurved are to protect health of healthy person and tocure disease of diseased person (ch. su. 30/26).

Person is said to be healthy when Dosha, Dhatu(digestive fire), Dhatvagni is in proper state and Mana (mind), Atma (soul), Indriya(motor and sensory organs) are in pleasant state (su. Su. 15/48). Definitiongiven by Acharya Sushrut is accepted by W.H.O. (world health organization).

According to W.H.O.

Health is a complete state of physical, mental, social andspiritual wellbeing not merely the absence of disease.

Now a day, disease related to skin is very common problem.According to Roxburgh book of common skin disease, about 10-15% of persons aresuffering from dermatitis. Due to any type of skin deformity, person has toface physical, mental and social problems. Under dermatological disorders, Ek-kushtha(psoriasis) is commonly caused chronic skin disorder due to unknown reasons.

It is found in about 2% of people of the world. In Psoriasis, there isinflammation and disease spread at the rate of 10 times greater than that ofnormal skin. It affects people of all genders and castes. In this, there arePidika (pimples) and Chakkate (Rashes) in the skin, which are clearly differentfrom normal skin. Mostly it is found in head, upper back, lumbar region, arms,legs, especially in the outer surface of elbows and knees.

In Ayurved, all Twaka (dermatological) related disordersincluded under Kushtha. Due to various reasons, the natural color of the skingets distorted due to leprosy. In case if proper treatment is not provided thenentire body of the patient gets affected.

Skin also has special significance like other organs. It isthe natural protective shield of the body which prevents various pathogeniccauses like bacteria, viruses etc from entering the body. The first visibleorgan is skin and it covers whole extremities of the body.

**BASIS OF TOPICSELECTION**

In the present era,dermal disorder is a serious problem. This disease affects a person not onlyphysically but mentally as well. In terms of beauty skin is very important, butpsoriasis is a skin disorder whose effects are seen in a person confidence andsocial activities. Psoriasis is one of the most common dermatologic diseases,affecting up to 1-2% of the worldâ€™s population. It occurs in all age groups andabout equally in men and women. The main cause for the origin of disease isirregular eating habits, heavy diet etc.

**BASISOF MEDICINE SELECTION**

1.   In Ayurveda, various formulations aredescribed for the treatment of leprosy in which Sushrutokta Aragvadhadigana hasbeen selected for the treatment of Psoriasis.

2.   Most of the constituent substances ofthis medicinal formulation having Bitter, astringent taste, Ushna Virya andKatu Vipaka which helps on balancing Kapha Dosha. Balancing Vata Dosha byhaving properties like Ushna Virya and Katu Vipaka. Therefore this medicinalformulation will be beneficial in the treatment of Psoriasis.

3.   In modern medical science, Psoriasis hasbeen called as incurable.

4.   Steroid and immunosuppressive drugs areused for its treatment from which patient gets immediate benefit but aftersometime the disease arises again. Using of these drugs doesnâ€™t completelyreduce the disease.

5.   All components of the selected drugsubstance are easily accessible.

Detailed Description: Not available

Recruitment & Eligibility

Status: Not Yet Recruiting

Sex: All

Target Recruitment: 60

Inclusion Criteria

1.Patients of age group between16 years to 60 years.
2.Sex- Male and Female both.
3.Symptoms mentioned in Ayurved and modern Texts.

Exclusion Criteria

1.Patients of age group below 16 years and above 60 years.
2.Pregnancy.
3.Duration of disease- more than 10 years.
4.Patients who loses their immunity power.
5.Patients of Kushtha.
6.Patients with other systemic disorders like chronic cardiac illness, tuberculosis, endocrine disorders, severe hypertension, bleeding diathesis.
7.Cancer, hepatitis, HIV.

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To assess the efficacy of Aragvadhadi gana ghanvati and virechan karma in the management of Psoriasis	90 days or 3 months

Secondary Outcome Measures

Name	Time	Method
As There Is Physically And Mentally Health Satisfaction So It Improves the Quality of Life	90 days or 3 month

Trial Locations

Locations (1): Shri Khudadad Doongaji Government Ayurved Hospital Raipur CG
🇮🇳
Raipur, CHHATTISGARH, India
Shri Khudadad Doongaji Government Ayurved Hospital Raipur CG
🇮🇳Raipur, CHHATTISGARH, India
Dr Srishti Chandrakar
Principal investigator
8109694056
srishtichandrakar03@gmail.com