Study of two different doses of Tranexamic acid given intravenously to reduce blood loss in spine surgeries.
Not Applicable
- Conditions
- Health Condition 1: 8- Other Procedures
- Registration Number
- CTRI/2023/11/059988
- Lead Sponsor
- Department of Anesthesia Government Medical College Surat
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Patients scheduled for spine surgery.
Patients belonging to ASA class 1,2 and 3.
Exclusion Criteria
Patient who are allergic to tranexamic acid.
Patients with altered clotting factors, coagulation profile, coagulation disorders etc.
Patients with neurosurgical disorders, epilepsy and visual disturbance.
Patients with deep vein thrombosis and thromboembolism.
Patients with major hepatorenal dysfunction.
Patients with major cardiopulmonary dysfunction,
Ischemic Heart Diseases, Angina.
Patients taking medications like blood thinners, antiplatelet drugs, anti-coagulants, fibrinolytics drugs.
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Total intraoperative blood loss. <br/ ><br> <br/ ><br>Requirement of blood and blood products in 24 hours. <br/ ><br>Timepoint: 24 hours. <br/ ><br>
- Secondary Outcome Measures
Name Time Method Assessment of: <br/ ><br> <br/ ><br>Hemoglobin, Haematocrit and PT INR values pre-operatively and Hemoglobin and Haematocrit <br/ ><br> <br/ ><br>24 hours post-operatively. Hemodynamic parameters. <br/ ><br> <br/ ><br>Adverse effects/side effects if any.Timepoint: 24 hours.