Evaluation of Different Disease Control Indices in Children With Asthma and Rhinitis
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 1,000
- 试验地点
- 1
- 主要终点
- Evaluation of Different Disease Control Indices in Children With Asthma and Rhinitis
研究概览
简要总结
In this study will be consecutive enrolled children with asthma (classified according to GINA guidelines) and rhinitis (classified by ARIA guidelines); the investigators will research clinical personal and parental history regarding allergic diseases, exposition to passive smoking and interpretate hematochemical parameters markers of atopy. Skin Prick Tests will be performed. In this study the investigators will evaluate lung function parameters (spirometry with bronchial reversibility test and exercise induced bronchoconstriction, oscillometry, respiratory plethysmography, etc.), airway inflammatory indices such as exhaled nitric oxide at different flows, exhaled and nasal temperature, nasal cytology.
The aim of the study will be to evaluate possible correlation between these different parameters and clinical status of the patients.
详细描述
Each patients will be evaluated by spirometry and then he will undergo exercise challenge in order to evaluate exercise-induced bronchoconstriction as a marker of asthma control. The test of the challenge will be correlate with childhood Asthma control test score,levels of control (GINA classification)and the different markers of airway inflammation and atopy.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 5 Years 至 —（Child, Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •patient with asthma and rhinitis
排除标准
- •age <5 years
- •chronic respiratory diseases
结局指标
主要结局
Evaluation of Different Disease Control Indices in Children With Asthma and Rhinitis
时间窗: Evaluation of Different Disease Control Indices in Children With Asthma and Rhinitis
次要结局
未报告次要终点
研究者
Boner Attilio
full professor
Universita di Verona