Tranexamic Acid to Prevent Operation in Chronic Subdural Hematoma
- Conditions
- Chronic subdural hematoma, chronisch subduraal hematoom, tranexamic acid, tranexaminezuur, burr-hole drainage, boorgatdrainage
- Registration Number
- NL-OMON29498
- Lead Sponsor
- Academic Medical Center Amsterdam
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Not specified
- Target Recruitment
- 140
Inclusion Criteria
· Age 50 years and above;
· On CT and/or MRI confirmed cSDH (isodense or hypodense subdural collection, uni- or bilateral);
Exclusion Criteria
· Primary surgical treatment based on one or more of the following symptoms or parameters: medically intractable headache, midline shift >10mm, imminent death within 24 hours;
· Structural causes for subdural haemorrhage, e.g. arachnoid cysts, cortical vascular malformations and a history of cranial surgery <1year;
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1. Number of patients requiring surgery for cSDH within 12 weeks;<br /><br>2. Quality of life at 12 weeks, measured with the Short Form Health Survey (SF-36) questionnaire.<br>
- Secondary Outcome Measures
Name Time Method