Surgical Prevention of Atrial Fibrillation in Patients With Rheumatic Mitral Valve Lesion and Left Atrium Enlargement
Not Applicable
Completed
- Conditions
- Rheumatic Heart DiseaseAtrial Fibrillation
- Registration Number
- NCT02474108
- Lead Sponsor
- Meshalkin Research Institute of Pathology of Circulation
- Brief Summary
This study evaluates the safety and efficiency of surgical prevention of atrial fibrillation in patients with valvular heart disease and left atrium enlargement
- Detailed Description
Preservation or appearance of AF(atrial fibrillation) after mitral valve surgery substantially reduce the number of excellent and good results of the operation in the long-term period, causing circulatory insufficiency, increased pulmonary hypertension, increasing the risk of thromboembolic events and stroke.
Significant predictors of AF after surgery are the initial size of the left atrium more than 6.0 cm, stenotic lesions and rheumatic genesis of mitral defect. 80% of patients in this group had AF during the first year after operation.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 40
Inclusion Criteria
- rheumatic mitral valve lesion
- the absence a history of AF
- sinus rhythm
- left atrium size more than 6.0 cm
Exclusion Criteria
- refusal to participate in the study
- aortic stenosis / regurgitation
- coronary atherosclerosis
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Primary Outcome Measures
Name Time Method composite outcome measure of complications up to 1 year
- Secondary Outcome Measures
Name Time Method number of participants with freedom from AF according to the long-term ECG monitoring 1 year transport function of the left atrium according to TTE (transthoracic echo) 1 year
Trial Locations
- Locations (1)
MeshalkinRI
🇷🇺Novosibirsk, Russian Federation
MeshalkinRI🇷🇺Novosibirsk, Russian Federation