Q10 supplementation on oxidative stress

Not Applicable

• Conditions: Traumatic patients under mechanical ventilation.; Diffuse traumatic brain injury; S06.2X

• Registration Number: IRCT20171221037983N4
• Lead Sponsor: Oroumia University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 25 March 2019

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

Traumatic patients under mechanically Ventilation
patients with 18-65 years
patients admitted to intensive care unit for at least 7 days

Exclusion Criteria

No Contraindication of Intestinal Nutrition
diabetic patients
Acute and chronic renal failure
GCS less than 9

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Oxidative stress was evaluated based on SOFA score (the sequential organ failure assessment score) and serum IL-6 (IL6). Timepoint: before and 7 days after intervention. Method of measurement: SOFA score was measured using a questionnaire and serum IL6 level based on ELISA method.

Secondary Outcome Measures

Name	Time	Method
Mortality. Timepoint: seven days after intervention. Method of measurement: The death of the patient in hospital (yes/no).;Mechanical ventilation duration. Timepoint: From admission to patient discharge. Method of measurement: Mechanical ventilation duration in days.;Duration of hospitalization. Timepoint: From admission to patient discharge. Method of measurement: duration of hospitalization in days.