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A Study of Participants With Non-Valvular Atrial Fibrillation (NVAF) Treated or Untreated With Oral Anticoagulant in the National Cerebral and Cardiovascular Center (NCVC) in Japan

Completed
Conditions
Non-Valvular Atrial Fibrillation (NVAF)
Registration Number
NCT05027061
Lead Sponsor
Bristol-Myers Squibb
Brief Summary

The purpose of this observational study is to understand real-world oral anticoagulants (OAC) (warfarin, apixaban, dabigatran, edoxaban and rivaroxaban) usage for non-valvular atrial fibrillation (NVAF) patients.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
11776
Inclusion Criteria

• Participants received medical treatment for NVAF between 10-Jan-2012 and 31-Aug-2020.

Exclusion Criteria
  • Had no data of serum creatinine in the participant's medical records
  • Had no data of body weight in the participant's medical records
  • Were given oral anticoagulant (OAC) for treatment of diseases other than atrial fibrillation (AF)

Other protocol-defined inclusion/exclusion criteria apply.

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Distribution of outcomes of NVAF participants: Pulse rateAt Baseline
Distribution of socio-demographic characteristics of NVAF participants: Age groupAt Baseline
Distribution of socio-demographic characteristics of NVAF participants: HeightAt Baseline
Distribution of outcomes of NVAF participants: Degree of life freedomAt Baseline
Distribution of clinical characteristics of NVAF participants: Risk factors for bleedingAt Baseline
Distribution of medication prescribed during baseline: angiotensin-converting enzyme inhibitor (ACE)At Baseline
Distribution of medication prescribed during baseline: Antiarrhythmic drugAt Baseline
Distribution of medication prescribed during baseline: H2-receptor antagonistAt Baseline
Distribution of clinical characteristics of NVAF participants: ComorbiditiesAt Baseline
Specialization of the treating physicianAt Baseline
Distribution of socio-demographic characteristics of NVAF participants: GenderAt Baseline
Distribution of outcomes of NVAF participants: Systolic and diastolic blood pressureAt Baseline
Distribution of medication prescribed during baseline: angiotensin-receptor blocker (ARB)At Baseline
Distribution of socio-demographic characteristics of NVAF participants: Body weightAt Baseline
Distribution of outcomes of NVAF participants: Drinking informationAt Baseline
Distribution of outcomes of NVAF participants: Smoking informationAt Baseline
Distribution of outcomes of NVAF participants: Hospitalization/outpatient statusAt Baseline
Distribution of clinical characteristics of NVAF participants: Risk factors for strokeAt Baseline
Distribution of outcomes of NVAF participants: OAC prescription and administration statusAt Baseline
Distribution of medication prescribed during baseline: StatinAt Baseline
Distribution of medication prescribed during baseline: P2Y12 inhibitorAt Baseline
Distribution of medication prescribed during baseline: Other antiplatelet drugsAt Baseline
Distribution of medication prescribed during baseline: Other anticoagulantsAt Baseline
Distribution of socio-demographic characteristics of NVAF participants: Body mass index (BMI)At Baseline
Distribution of outcomes of NVAF participants: Internal medical device informationAt Baseline
Distribution of medication prescribed during baseline: calcium antagonistAt Baseline
Distribution of medication prescribed during baseline: proton pump inhibitor (PPI)At Baseline
Distribution of medication prescribed during baseline: aspirinAt Baseline
Distribution of medication prescribed during baseline: P-glycoprotein inhibitorAt Baseline
Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

Local Institution

🇯🇵

Tokyo, Japan

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