Evaluating the effect of simultaneous use of persica and chlorhexidine on chemotherapy-induced oral ulcers of children between 6 and 12 year old
Phase 2
- Conditions
- Chemotherapy-induced mucositis.Other and unspecified lesions of oral mucosa
- Registration Number
- IRCT2014060117935N1
- Lead Sponsor
- Vice Chancellor for Research of Shahid Sadoughi University of Medical Sciences of Yazd
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 40
Inclusion Criteria
age range of 6-12 years; history of hematologic malignancies with the same treatment protocol; no history of sensitivity to any substances; no history of asthma, allergic rhinitis and dermatitis; no need of radiotherapy; written informed consent obtained from parents or legal guardian.
Exclusion criteria: occurrence of any infection; occurrence of sensitivity to mouth-rinses.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Incidence of mucositis. Timepoint: Day 1 (before intervention), 8 and 15. Method of measurement: World Health Organization (WHO) grading.;Severity of mucositis. Timepoint: Day 1 (before intervention), 8 and 15. Method of measurement: World Health Organization (WHO) grading; Oral Assessment Guide (OAG) grading.
- Secondary Outcome Measures
Name Time Method Severity of pain. Timepoint: Day 1 (before intervention), 8 and 15. Method of measurement: Facial Image Scale.