The effect of ginger supplementation on pain and inflammatory factors
- Conditions
- osteoarthritis.Primary generalized (osteo)arthrosis
- Registration Number
- IRCT201112078321N1
- Lead Sponsor
- Yazd University of Medical Scieces
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 100
to complete the inform consent; the presence of medium knee pain between 40mm and 70 mm on a 100-mm visual analog scale (VAS) during the preceding 24 hours; the age between 50 and 70 years; absence of following conditions: inflammatory disease, metabolic disorder such as diabetes, dementia, rheumatoid arthritis, fibromyalgia, gout, cancer or other serious disease, signs or history of liver or kidney failure, asthma requiring treatment with steroids; treatment with oral corticosteroids within the prior 4 weeks; intraarticular knee depo-corticosteroids within the previous 3 months; prior treatment with immunosuppressive drugs such as penicillamine; arthroscopy of the target joint within the previous yea; significant injury to the target joint within the previous 6 months; fever >38 degree C at screening; allergy to ginger. Exclusion criteria: serious complications; consumption of vitamin-mineral supplements or other nutritional supplements; consumption of analgesics.
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Pain. Timepoint: before the intervention and 12 weeks after the end of treatment. Method of measurement: visual analoge scale.
- Secondary Outcome Measures
Name Time Method Some pro-inflammatory cytokins. Timepoint: before the intervention and after 12 weeks. Method of measurement: ELISA kit.