Multimodal Intervention Trial to reduce dementia and disability in india
Phase 4
- Conditions
- Health Condition 1: F068- Other specified mental disorders due to known physiological condition
- Registration Number
- CTRI/2023/07/055130
- Lead Sponsor
- TATA EDUCATION TRUST
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1.Participants of either gender who are above 55 years of age
2.Clinical Dementia Rating score of 0 or 0.5
Exclusion Criteria
1.Substantial cognitive decline, CDR > 0.5
2.Significant cardiopulmonary diseases.
3.History of major heart surgery (i.e., valve replacement, bypass surgery, angioplasty) in the past 6 months.
4.Malignancy.
5.End stage of renal disease requiring dialysis.
6.History of fracture, joint replacement, or spinal surgery in the last 6 months.
7.History of alcohol or substance dependence in last 12 months
8.Parkinsonâ??s disease
9.Neurological & psychological illness
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method COGNITO <br/ ><br>HMSE <br/ ><br>CDR <br/ ><br>ACE III (R) <br/ ><br>Feasibility MeasuresTimepoint: 6th & 12th month
- Secondary Outcome Measures
Name Time Method 1)Depressive symptoms will be assessed with Geriatric Depression Scale & Hamilton Depression Rating scale. <br/ ><br>2)Quality of life using WHO SF-36 questionnaire. <br/ ><br>3)Vascular and Metabolic risk factors will be assessed with blood pressure, anthropometric measurements and metabolic biomarkers through laboratory testing.Timepoint: 6th & 12th month