Study of Arthralgia and Vasomotor Symptoms in Japanese Postmenopausal Women Treated with Anastrozole
Not Applicable
- Conditions
- Postmenopausal breast cancers
- Registration Number
- JPRN-UMIN000002455
- Lead Sponsor
- Department of Surgery, Hyogo College of Medicine
- Brief Summary
PROs from 362 patients (92.6 %) were obtained. New or worsening from baseline of joint symptoms were reported by 260 patients (71.8 %). More than 90 % of the symptoms were mild or moderate. Multivariate analysis showed that a short time span after menopause [odds ratio (OR) 0.95, 95 % confidence interval (CI) 0.90-0.99; P = 0.02] and adjuvant chemotherapy (OR 2.29, 95 % CI 1.06-4.95; P = 0.03) were significant independent risk factors for joint symptoms.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- Female
- Target Recruitment
- 391
Inclusion Criteria
Not provided
Exclusion Criteria
Bilateral breast cancer Double cancer within 5 years after treatment
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Frequency of arthralgian and vasomotor symptoms.
- Secondary Outcome Measures
Name Time Method