Skip to main content
Clinical Trials/NCT06515756
NCT06515756
Completed
Not Applicable

The Effect of Three Different Bioceramic-Based Root Canal Sealers on Post-Operative Pain

Kırıkkale University1 site in 1 country120 target enrollmentJuly 4, 2023

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Postoperative Pain, Acute
Sponsor
Kırıkkale University
Enrollment
120
Locations
1
Primary Endpoint
Change in pain from 6 th hours to 30 days between root canal sealers
Status
Completed
Last Updated
last year

Overview

Brief Summary

Brief Summary: The purpose of this study was to evaluate the effect of MTA-Bioseal, GuttaFlow bioseal, and NeoSealer Flo calcium-silicate based root canal sealers on postobturation pain in teeth with asymptomatic irreversible pulpitis or chronic apical periodontitis undergoing single-visit root canal treatment.

The study tried to answer whether the type of sealer used altered the incidence and intensity of postobturation endodontic pain, whether pulp status affected the incidence and intensity of postobturation endodontic pain and whether there was no difference in analgesic intake by patients after a single-visit root canal treatment between the experimental groups.

Detailed Description

This prospective clinical study was reported pain levels experienced after obturation were similar for the different pulp statuses and root canal sealers tested. The participants with single-rooted teeth were included and divided into four groups according to the root canal sealer used. Then, the patients were divided into two subgroups according to pulp vitality. The postobturation pain scores were recorded after obturation on a visual analog scale (VAS) at 6, 12, 24, and 48 hours, and at 7 and 30 days. The level of pain experienced after obturation was similar for all root canal sealers in different pulp statuses. The results of the study showed that the bioceramic-based sealers tested can be used safely in clinical practice in terms of postobturation pain.

Registry
clinicaltrials.gov
Start Date
July 4, 2023
End Date
February 2, 2024
Last Updated
last year
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Sponsor
Kırıkkale University
Responsible Party
Principal Investigator
Principal Investigator

Ali Turkyilmaz

Asisstant Professor

Kırıkkale University

Eligibility Criteria

Inclusion Criteria

  • Good oral hygiene,
  • Not reporting pain before the appointment
  • Asymptomatic irreversible pulpitis caused by deep carious lesions (vital cases),
  • Asymptomatic primary apical periodontitis (non-vital cases).

Exclusion Criteria

  • Pregnancy,
  • Autoimmune diseases,
  • Uncontrolled diabetes,
  • Advanced periodontal disease (with 5 mm or more probing depth),
  • Patients requiring endodontic treatment for more than one tooth,
  • Unrestorable coronal destruction,
  • Incomplete root formation, systemic,
  • Allergic sensitivity to local anesthetic or NSAIDs.
  • ASA II patient
  • An analgesic or antibiotic intake the 7 days before the beginning of treatment

Outcomes

Primary Outcomes

Change in pain from 6 th hours to 30 days between root canal sealers

Time Frame: 6, 24, and 72 hours and at 7 and 30 days

All participants were asked to rate their perceived pain on the scale, with 0 indicating no pain and 10 indicating the highest possible pain. Pain levels were classified as none, mild (1 to 3), moderate (4 to 7), or severe (8 to 10).

Secondary Outcomes

  • Change in pain from 6 th hours to 30 days between diffrernt pulp status(6, 24, and 72 hours and at 7 and 30 days,)

Study Sites (1)

Loading locations...

Similar Trials