The value of bronchodilators and anti-inflammatory medication in patients with posttraumatic rib fractures, a multicenter prospective cohort study (RIB-Inhalation)

Recruiting

• Conditions: Multiple rib fractures

• Registration Number: NL-OMON25831
• Lead Sponsor: Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands

Brief Summary

one yet

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 28 February 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: Not specified
• Target Recruitment: 100

Inclusion Criteria

1) Age 16 years or older
2) Hospital admission with =3 rib fractures (CT-confirmed) after blunt chest trauma
3) Chest CT-scan within 24h after trauma
4) GCS score 15
5) Provision of informed consent by patient

Exclusion Criteria

1) Use of bronchodilators in the last week before trauma
2) Known pregnancy
3) Previous thoracic surgery (e.g., lung resection)
4) Previous pulmonary problems, requiring continuous oxygen at home pre-trauma
5) Congenital thoracic deformity (e.g., pectus excavatum, pectus carinatum, severe scoliosis, or kyphosis)
6) Planned transfer to other hospital during primary admission
7) Insufficient comprehension of the Dutch language to understand the study documents in the judgement of the treating physician or research team

Study & Design

• Study Type: Observational non invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Pneumonia during primary hospital admission

Secondary Outcome Measures

Name	Time	Method
- Pulmonary function (forced vital capacity and forced expiratory volume in 1 second),<br>- Occurrence of thoracic complications<br>- Occurrence of symptoms indicative of side effects of bronchodilators<br>- Hospital length of stay