Different Crystalloids on the Incidence of Acute Kidney Injury in Shock Patients
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 40
- 主要终点
- Incidence of acute kidney injury
研究概览
简要总结
Fluid resuscitation is important in shock therapy, but the choice of fluids, especially the choice of crystalloid is under debate. It is said that normal saline is related to hyperchloremia， which might lead to acute kidney injury. Thus the hypothesis of the study is to explicit whether balanced salt solution could reduce the incidence of acute kidney injury when compared with normal saline.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Single Group
- 主要目的
- Prevention
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Shock patients
排除标准
- •History of chronic renal failure
研究组 & 干预措施
Normal saline group
Shock patients who resuscitated with normal saline were enrolled between June, 2015-June.2016.
干预措施: Fluid resuscitation (Drug)
Balanced solution group
Shock patients who resuscitated with balanced solution were enrolled after June, 2016.
干预措施: Fluid resuscitation (Drug)
结局指标
主要结局
Incidence of acute kidney injury
时间窗: 28-day
Diagnosis of acute kidney injury
次要结局
- Usage of renal replacement of therapy(28-day)
研究者
Jingyuan,Xu
Principal Investigator
Southeast University, China