Different Crystalloids on the Incidence of Acute Kidney Injury in Shock Patients
Overview
- Phase
- Not Applicable
- Intervention
- Fluid resuscitation
- Conditions
- Shock
- Sponsor
- Southeast University, China
- Enrollment
- 40
- Primary Endpoint
- Incidence of acute kidney injury
- Last Updated
- 8 years ago
Overview
Brief Summary
Fluid resuscitation is important in shock therapy, but the choice of fluids, especially the choice of crystalloid is under debate. It is said that normal saline is related to hyperchloremia， which might lead to acute kidney injury. Thus the hypothesis of the study is to explicit whether balanced salt solution could reduce the incidence of acute kidney injury when compared with normal saline.
Investigators
Jingyuan,Xu
Principal Investigator
Southeast University, China
Eligibility Criteria
Inclusion Criteria
- •Shock patients
Exclusion Criteria
- •History of chronic renal failure
Arms & Interventions
Normal saline group
Shock patients who resuscitated with normal saline were enrolled between June, 2015-June.2016.
Intervention: Fluid resuscitation
Balanced solution group
Shock patients who resuscitated with balanced solution were enrolled after June, 2016.
Intervention: Fluid resuscitation
Outcomes
Primary Outcomes
Incidence of acute kidney injury
Time Frame: 28-day
Diagnosis of acute kidney injury
Secondary Outcomes
- Usage of renal replacement of therapy(28-day)