Impact of Fluid and Passive Leg Raising on Cardiac Output in Patients Undergoing Cardiac Surgery

Completed

• Conditions: Artificial Heart Device User

• Registration Number: NCT03179033
• Lead Sponsor: Sheba Medical Center

Brief Summary

Left Ventricular Assist Device (LVAD) implantation is a common surgical procedure in patients with end-stage heart failure. Optimal fluid management is essential for adequate postoperative treatment. It is important to identify which patients will benefit from fluid administration. Passive leg raising (PLR) is a validated dynamic method to predict fluid responsiveness in patients with heart failure by inducing a transient increase in cardiac preload. Objective: To investigate the role of PLR on the management of patients following LVAD implantation in the postoperative period.

Detailed Description

Not available

Study Timeline

• Study Start: 2016-10-19
• Status Verified: 2017-06
• Study First Submitted: 2017-06-05
• Study First Submitted QC: 2017-06-05
• Study First Posted: 2017-06-07
• Primary Completion: 2017-08-30
• Study Completion: 2017-08-30
• Last Update Submitted: 2018-01-17
• Last Update Posted: 2018-01-18

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 20

Inclusion Criteria

• Patients after VAD implantation

Exclusion Criteria

• Age under 18

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Responsiveness to passive leg raising in patients early after LVAD implantation	5 minutes	Change in LVAD flow due to passive leg raising

Trial Locations

Locations (1)

Sheba medical center; 🇮🇱 Ramat Gan, Israel