ISRCTN18300486Active, not recruitingUnknown
Magnetic resonance spectroscopy of 2-hydroxyglutarate for the identification of IDH mutations status in glioma
niversity of Edinburgh0 sites20 target enrollmentStarted: September 22, 2023Last updated:
Conditions
Trial Snapshot
- Phase
- Unknown
- Status
- Active, not recruiting
- Sponsor
- Enrollment
- 20
Study Overview
Brief Summary
No summary available.
Study Design
- Study Type
- Observational
Eligibility Criteria
- Sex
- All
Inclusion Criteria
- •1. Radiological appearances consistent with diffuse glioma or tissue proven diffuse glioma
- •2. A signed and dated, informed consent must be obtained prior to study participation
- •3. Adults aged 18 - 75 years
- •4. WHO performance status 0 – 1
- •5. Measurable disease in the case of post-surgery subjects
Exclusion Criteria
- •1. Participants for whom MRI is contraindicated
- •2. Patients with tumours in locations that preclude tissue sampling by biopsy or surgical resection.
- •3. Patients whose co-morbidities or functional status precludes tissue acquisition by biopsy or surgical resection.
Investigators
Similar Trials
Completed
Not Applicable
Insomnia Magnetic Resonance Spectroscopy (MRS) imaging sleep studyACTRN12612000050853niversity of Sydney47
Not yet recruiting
Not Applicable
Magnetresonancespectroskopic measurement of ethanol in the human braihealthy participantsDRKS00012326Institut für Rechtsmedizin4
Completed
Not Applicable
Magnetic Resonance Spectroscopy in Acid Sphingomyelinase DeficiencyNiemann-Pick diseaseacid sphingomyelinase deficiency10021605NL-OMON53399Academisch Medisch Centrum34
Active, not recruiting
Not Applicable
itrous Oxide and Functional Magnetic Resonance Imaging to investigate cerebral regional blood flow, cerebral metabolism and neuronal activity. - Nitrous Oxide and Functional MRIThis is part of a series of studies investigating the potential therapeutic use of low dose nitrous oxide in the treatment of cerebral vasospasm, a condition which occurs following brain injury and stroke. We are looking to see if the increased blood flow to the brain seen with nitrous oxide is caused by an increase in cerebral metabolism. This would need to be excluded if nitrous oxide is to be considered as a potential treatment.EUCTR2009-018181-36-GBniversity of Nottingham
Not yet recruiting
Not Applicable
31P Magnetic Resonance Spectroscopic Imaging of brain tumourshersen tumorenbrain tumourglial tumourNL-OMON32708niversitair Medisch Centrum Sint Radboud20
