Photoscreening for Retinoblastoma

Not Applicable

• Conditions: Retinoblastoma
• Interventions: Device: Photoscreening -

• Registration Number: NCT04344652
• Lead Sponsor: Phoenix Children's Hospital

Brief Summary

Retinoblastoma is the most common pediatric eye malignancy and manifests between 1 and 5 years of age. The tumor is most often diagnosed by leukocoria ( white reflex in the pupil). There is often a significant delay in diagnosis and early diagnosis enables good life prognosis and better vision outcome.There is currently not a standardized screening protocol for detection of retinoblastoma. Vision screening methods are recommended for children 3-5 years of age. The investigators are attempting to use instrument based screening started from birth to detect leukocoria.

Detailed Description

Not available

Study Timeline

• Status Verified: 2020-04
• Study First Submitted: 2020-04-09
• Study First Submitted QC: 2020-04-13
• Last Update Submitted: 2020-04-13
• Study First Posted: 2020-04-14
• Last Update Posted: 2020-04-14
• Study Start: 2020-06-01
• Primary Completion: 2021-05-31
• Study Completion: 2021-05-31

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 76

Inclusion Criteria

• Age birth to 10 years
• Informed consent given by parent or legal guardian

Exclusion Criteria

• None

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
Photoscreening	Photoscreening -	Photoscreening of patients 0 to 10 years of age

Primary Outcome Measures

Name	Time	Method
Reliability to detect leukocoria	1 year	Testing the reliability of the app to detect leukocoria with good sensitivity and specificity