FDG-PET and cMRI for the differential diagnosis of parkinson's disease and atypical parkinson syndroms

Recruiting

• Conditions: G23.2; G23.1; G23.9; G20; Parkinson disease; Multiple system atrophy, parkinsonian type [MSA-P]; Degenerative disease of basal ganglia, unspecified; Progressive supranuclear ophthalmoplegia [Steele-Richardson-Olszewski]

• Registration Number: DRKS00016574
• Lead Sponsor: Klinik für Neurologie und NeurophysiologieUniversitätsklinikum Freiburg

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2019-01-28
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 314

Inclusion Criteria

Presentation of an atypical parkinson syndrom in one of the study centers
- Symptoms / anamnesis suggestive for an atypical parkinson syndrom
- age > 18 years
- the patient has recieved an MRI and a FDG-PET of the brain

Exclusion Criteria

No possibility for oral and written consent

Study & Design

• Study Type: observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The diagnostic accuracy of the MRI and the FDG-PET in the diseases mentioned above (ICD-10). (Measured in sensitivity and specifity, comparison of FDG-PET and MRI by receiver operating characteristics (ROC)-Analysis)

Secondary Outcome Measures

Name	Time	Method
- Evaluation of a potential synergistic value of both imaging modalities<br>- Correlation of the imaging findings with clinical parameters