MedPath

Comparison of 6 months Isoniazid v/s 3 months Isoniazid - Rifampicin Therapy for Prevention of Tuberculosis in Children Suffering from Latent Tuberculosis Infectio

Phase 3
Completed
Conditions
Health Condition 1: A150- Tuberculosis of lungHealth Condition 2: A150- Tuberculosis of lung
Registration Number
CTRI/2022/02/040539
Lead Sponsor
DR SHIVANGI SINHA
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
Not specified
Target Recruitment
64
Inclusion Criteria

children (6-14years)with LTBI living with sputum smear positive adult TB patients undergoing DOTS

Exclusion Criteria

children in contact with adults having multidrug resistant TB (MDR-TB) or Extensively drug resistanT TB(XDR-TB).

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
The proportion of children with LTBI developing Tuberculosis at 9 months after receiving treatment with 3 months HR v/s 6 months INH will be calculated and compared. <br/ ><br>Timepoint: 2 years
Secondary Outcome Measures
NameTimeMethod
both groups will be compared in terms of adverse effectsTimepoint: 2 years
© Copyright 2025. All Rights Reserved by MedPath