Effect of Antibiotics in superficial and deep infection after cholecystectomy

Not Applicable

Conditions: Cholecystitis.
Acute cholecystitis
K81.0

Registration Number: IRCT20201023049120N1

Lead Sponsor: Tehran University of Medical Sciences

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Complete

Sex: All

Target Recruitment: 60

Inclusion Criteria

Patients who are classified as mild or moderate cholecystitis according to the Tokyo 2018 guideline
Referred to the emergency department of Sina and Amir Alam hospitals from the March 21th, 2019 to March 20th, 2021
Age over 18 years

Exclusion Criteria

Patients with Severe cholecystitis (grade III)
Patients who have had abdominal pain for more than 5 days
Patients who have been diagnosed with common bile duct stones during preoperative or postoperative examinations
Patients diagnosed with cholangitis include patients with concomitant pancreatitis
Cirrhotic patients
Patients with hepatobiliary system cancers
Patients with acquired or primary immunodeficiency
Patients with antibiotic susceptibility to beta-lactams
Patients with cholecystitis since diagnosis acute mild or moderate for them until surgery more than 48 interruptions
Pregnant or lactating patients
Patients who did not consent to participate in this study

Study & Design

Study Type: interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The rate of infection at the operation site. Timepoint: Up to 30 days after surgery(At the time of hospitalization daily and every two weeks thereafter). Method of measurement: Presence of purulent discharge from the wound, positive culture of wound discharge sampled by sterile method with one or more of the following symptoms: pain, tenderness, local swelling, warmth or redness of the wound. The diagnosis of SSI is made by the patient's professor or resident.;The rate of deep infection. Timepoint: Up to 30 days after surgery (At the time of hospitalization daily and every two weeks thereafter). Method of measurement: Presence of purulent discharge from the wound, positive culture of wound discharge sampled by sterile method with one or more of the following symptoms: pain, tenderness, local swelling, warmth or redness of the wound. The diagnosis of SSI is made by the patient's professor or resident.

Secondary Outcome Measures