Vasoactive peptides: regional plasma concentrations and correlation with cardiac haemodynamic status.

Not Applicable

Recruiting

• Conditions: Cardiovascular disease; Cardiovascular - Other cardiovascular diseases

• Registration Number: ACTRN12606000136505
• Lead Sponsor: Professor Mark Richards, Professor in Medicine, Christchurch School of Medicine and Health Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2006-04-20
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

1) Individuals requiring diagnostic or interventional coronary angiogram.

Exclusion Criteria

:1) Clinical contraindication to invasive coronary angiographic or percutaneous procedures2) Hypotension (systolic blood pressure<100mmHg)3) Anuria4) Requirement for emergency percutaneous intervention where obtaining research samples might delay treatment.

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To document the regional plasma concentrations of vasoactive peptides (including natriuretic peptides, angiotensin II, aldosterone and urocortin 1) in individuals with a spectrum of cardiovascular disease at a single time point.[]

Secondary Outcome Measures

Name	Time	Method
To document the transcardiac gradient of vasoactive neurohormones across a spectrum of cardiac and renal function at a single time point.[]