Postoperative fluid management after major abdominal surgery: Goal directed therapy versus Ultrasound guided volume assessment
试验速览
- 阶段
- 4 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 92
- 试验地点
- 1
- 主要终点
- Point of Care Ultrasound and VExUS scoring will be a more sensitive tool to detect fluid responsiveness and early overload in postsurgical patients
研究概览
简要总结
Postoperative fluid management remains a cornerstone in the management of patients undergoing major abdominal surgery and their uneventful outcome.In this study we will manage the fluid status of the patients postoperatively using goal directed therapy and by ultrasound guided volume assessment and VExUS scoring.We expect that,patients with postoperative fluid management guided by the VExUS scoring will have a more optimized fluid support and are expected to have less morbidity, earlier return of gut function, early mobilization and enteral nutrition, lower incidence of systemic volume overload such as pulmonary congestion and respiratory impairment and improved end organ perfusion.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Participant and Investigator Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •Patients aged between 18 to 60 years, all genders, ASA physical status I and II with no associated comorbidities, having no surgical complications within the study period and no sepsis or cardiogenic shock.
排除标准
- •Patients refuse to give consent, patients having known cardiac and respiratory disorders, contraindications or inability to initiate indwelling catheters, patients with major intra operative hemodynamic or cardiac events, patients requiring elective or emergency post operative ventilation.
结局指标
主要结局
Point of Care Ultrasound and VExUS scoring will be a more sensitive tool to detect fluid responsiveness and early overload in postsurgical patients
时间窗: 72 hours postoperatively
次要结局
- Assessment of hypoperfusion or fluid overload events(72 hours postoperatively)
- Requirement of vasopressors and diuretics to achieve perfusion goals(72 hours postoperatively)
- Incidence of organ dysfunction such as lung congestion, AKI, ileus and altered liver function all attributed to perfusion pressure mismatch(72 hours postoperatively)
研究者
Arpan Chakraborty
Institute of Post Graduation Medical Education and Research,Kolkata