A Precision Medicine Approach to Target Engagement for Emotion Regulation
Overview
- Phase
- N/A
- Intervention
- Not specified
- Conditions
- Emotional Regulation
- Sponsor
- Matthew Southward
- Enrollment
- 390
- Locations
- 1
- Primary Endpoint
- Changes in Positive and Negative Affect Schedule-Short Form
- Status
- Recruiting
- Last Updated
- 2 years ago
Overview
Brief Summary
The proposed study is designed to first test whether teaching people personalized or standardized emotion regulation skills leads to greater decreases in daily negative emotion intensity. Second, using data from an initial sample, the investigators will prospectively assign an independent sample of participants to receive their predicted optimal or non-optimal skills to determine if it is feasible and efficacious to match participants to the most appropriate training condition. Results of these studies may identify the mechanisms by which emotion regulation interventions impact emotional functioning and allow for the development of personalized, evidence-based, and scalable emotion regulation interventions.
Investigators
Matthew Southward
Research Assistant Professor
University of Kentucky
Eligibility Criteria
Inclusion Criteria
- •Elevated emotion dysregulation
Exclusion Criteria
- •Lack of proficiency in English
- •No access to smartphone
- •Conditions requiring greater than outpatient care
Outcomes
Primary Outcomes
Changes in Positive and Negative Affect Schedule-Short Form
Time Frame: 7 times per day for 42 days
A self-report measure designed to assess the intensity of momentary negative affect. Scores range from 1 to 5, with higher scores indicating greater negative affect and lower scores indicating less negative affect.
Secondary Outcomes
- Changes in Hamilton Depression Rating Scale(Once every 2 weeks for 6 weeks (4 times total))
- Changes in emotion regulation effectiveness(7 times per day for 48 days)
- Changes in Hamilton Anxiety Rating Scale(Once every 2 weeks for 6 weeks (4 times total))
- Changes in Five-Factor Model Score Sheet(Once every 2 weeks for 6 weeks (4 times total))
- Changes in Ways of Responding Scale(Once every 2 weeks for 6 weeks (4 times total))
- Changes in Opposite to Emotion Action Task(Once every 2 weeks for 6 weeks (4 times total))
- Changes in Breath-Counting Task(Once every 2 weeks for 6 weeks (4 times total))