Mouse Allergen and Asthma Intervention Trial
试验速览
- 阶段
- 3 期
- 状态
- 已完成
- 入组人数
- 361
- 试验地点
- 4
- 主要终点
- change in asthma symptoms
研究概览
简要总结
The MAAIT is a randomized, controlled trial of a home intervention to reduce mouse allergen exposure in mouse allergic children with asthma and mouse allergen exposure. Participants will be randomized to either the Integrated Pest Management (IPM) Group or the Education Group. The IPM Group will receive professional mouse abatement, education, two HEPA filters, allergen-proof mattress and pillow encasements, and targeted cleaning. The Education Group will receive education about IPM at the beginning of the trial and then after completion of the trial, will receive the IPM intervention. Participants will be followed for 12 months.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 6 Years 至 17 Years（Child）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •persistent asthma
- •exacerbation, previous 12 months
- •evidence of mouse sensitization
- •high levels of mouse allergen in home
- •ages 5-17 years
排除标准
- •intermittent asthma
- •no exacerbation in previous 12 months
- •not sensitized to mouse
- •low or undetectable mouse allergen in home
- •other lung disease aside from asthma
结局指标
主要结局
change in asthma symptoms
时间窗: 0, 3, 6, 9, 12 months
days of asthma symptoms
次要结局
未报告次要终点
研究者
Elizabeth Matsui
Associate Professor
Johns Hopkins University