Effect of direct renin inhibitor(Aliskiren) in chronic heart failure patient with hypertensio
- Conditions
- chronic heart failure
- Registration Number
- JPRN-UMIN000005719
- Lead Sponsor
- Anjo Kosei Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 100
Not provided
1)Patient who has hypersensitivity and the past in direct renin inhibitor 2)Patient treated by ACE inhibitor 3)Patient with poor control of diabetic mellitus(HbA1c 9% or more) 4)Patient with unstable angina pectoris or who has the past history of acute myocardial infarction and cerebral infarction within three months 5)Patient with LVEF<30% 6)Patient who has serious liver disease (child classification C or more) 7)Patient who has serious kidney disease 8)Patient who is taking medicine of contraindication of using together 9)Woman who has possibility of pregnancy or getting pregnant 10)Breast-feeding woman 11)Patient with hyperkalemia(5.5mEq/L or more) 12)Patient of eGFR<30mL/min/1.73 m2 13)Additionally, patient who judged to be improper as testee
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Changes in serum brain natriuretic peptide level
- Secondary Outcome Measures
Name Time Method Changes in LVEF,blood pressure,PRA,plasma aldosterone level,serum potassium level,eGFR,serum creatinine level,albuminuria,uric acid level