The effect of immediate cessation of intravenous oxytocin post birth on postpartum haemorrhage in spontaneous vaginal delivery following induction of labour with oxytocin: a comparison of three regimes.

Phase 2

• Conditions: Postpartum blood loss; Reproductive Health and Childbirth - Childbirth and postnatal care

• Registration Number: ACTRN12615001173583
• Lead Sponsor: Curtin University School of Nursing Midwifery and Paramedicine

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2015-11-02
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: ot yet recruiting
• Sex: Female
• Target Recruitment: 312

Inclusion Criteria

Women would be included in the study if they:
Are more than or equal to 16 years old.
Receive intrapartum oxytocin for induction of labour.
Have a singleton pregnancy.
Are more than or equal to 37 weeks gestation.
Have a spontaneous vaginal delivery.

Exclusion Criteria

Women would be excluded from the study if they:
Are <16 years old.
Have a multiple pregnancy.
Are <37 weeks gestation.
Commence intravenous oxytocin as part of the postpartum haemorrhage regime.
Have an assisted vaginal delivery.
Have a caesarean section.
Have their intravenous oxytocin ceased before delivery.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Total measured blood loss (all bedding etc weighed in conjunction with actual blood loss) in women who have intravenous oxytocin ceased after completion of the third stage of labour.<br><br>Please note that intravenous oxytocin is generally titrated up in labour from 12 to 108 mls per hour depending on the strength and length of contractions. For analysis women will be grouped into a low medium and high group according to the maximum amount of oxytocin reached[2 hours after the completion of the third stage of labour]

Secondary Outcome Measures

Name	Time	Method
The proportion of women who have a postpartum haemorrhage (blood loss greater than or equal to 500mls), when intravenous oxytocin is ceased at 15, 30 or 60 minutes following completion of the third stage of labour, for women who receive syntometrine management of the third stage of labour. Syntometrine is not given to women who <br>have high bood pressure-67% in our hospital recieves Syntometrine. It is the prefered drug for third stage of labour[2 hours after the completion of the third stage of labour];The proportion of women who have a postpartum haemorrhage (blood loss greater than or equal to 500mls), when intravenous oxytocin is ceased at 15, 30 or 60 minutes following completion of the third stage of labour, for women who receive syntocinon management of the third stage of labour<br>Syntocinon is given in 33% of women in our hospital for third stage labour. Generally this is given to women who have raised blood pressure/cardiac abnormalities.[2 hours after the completion of the third stage of labour]