Genetic Information and Dietary Intake Behaviour

Early Phase 1

Completed

• Conditions: Healthy
• Interventions: Other: Dietary advice with genetic information; Other: General dietary recommendations

• Registration Number: NCT01353014
• Lead Sponsor: University of Toronto

Brief Summary

This study's primary objective is to determine if providing individuals with personal genetic information impacts dietary intake behaviour. Specifically, the investigators will be examining whether providing dietary advice based on genes that affect the metabolism of or sensitivity to caffeine, vitamin C, sugar and sodium will impact the intake of these dietary components. The study hypothesis is that providing dietary advice based on genetics will impact dietary behaviour to a greater extent than general dietary recommendations.

Detailed Description

Not available

Study Timeline

• Study Start: 2011-05
• Study First Submitted: 2011-05-04
• Study First Submitted QC: 2011-05-11
• Study First Posted: 2011-05-12
• Primary Completion: 2011-12
• Study Completion: 2012-09
• Status Verified: 2014-06
• Last Update Submitted: 2014-06-29
• Last Update Posted: 2014-07-01

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 138

Inclusion Criteria

• 20-35 year old participants from the Toronto Nutrigenomics and Health Study

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Exclusion Criteria

• pregnancy or nursing
• vitamin C supplement users
• caffeine intake < 100 mg/day
• total sugars intake < 10% energy
• sodium intake < 1500 mg/day

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Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
Dietary advice with genetic information	Dietary advice with genetic information	This group will receive dietary advice for caffeine, vitamin C, sugar and sodium based on genetic information.
General dietary recommendations	General dietary recommendations	This group will receive general dietary recommendations for caffeine, vitamin C, sugar and sodium from recognized health institutions (caffeine: Health Canada; sugar: the World Health Organization; vitamin C and sodium: the Institute of Medicine).

Primary Outcome Measures

Name	Time	Method
Change from Baseline in Dietary Intake at 3 months	3 months	We will assess dietary intakes of caffeine (mg), vitamin C (mg), sugar (g and % energy) and sodium (mg) using Food Frequency Questionnaires (FFQ). An FFQ will be administered at baseline to determine dietary habits before dietary advice is given to either group (control or intervention). A second FFQ will be administered 3 months after the dietary advice is given, to examine if any changes were made to dietary intake in the short-term.
Change from Baseline in Dietary Intake at 12 months	12 months	A third FFQ will be administered 12 months after the dietary advice is given, to examine if any long-term dietary changes were made in intakes of caffeine (mg), vitamin C (mg), sugar (g and % energy) and sodium (mg).

Trial Locations

Locations (1)

University of Toronto; 🇨🇦 Toronto, Ontario, Canada