Pre-operative Rotational Thromboelastometry to predict massive transfusion in liver transplant surgeries: a prospective study
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 108
- 试验地点
- 1
- 主要终点
- A deranged maximum clot firmness value will predict the incidence of massive blood transfusion in patients undergoing liver transplant surgery.
研究概览
简要总结
This is a prospective, case control study designed with 108 patients, of male and female genders, to investigate whether the maximum clot firmness value of the pre-operative ROTEM graph can be used to predict the incidence of massive transfusion in patients undergoing liver transplant surgeries.
The rotational thromboelastometry or ROTEM is a laboratory visco-elastic test used to asses the clotting functions of the blood sample. Maximum clot firmness is one of the values derived from this graph and will be used in this study.
The ROTEM test will be done on the pre-operative day. The incidence of massive transfusion in the surgery will be followed up.
Other information regarding incidence of sepsis, acute kidney injury, early graft dysfunction and mortality will be subsequently followed up in the post operative period.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18.00 Year(s) 至 99.00 Year(s)（—）
- 性别
- All
入选标准
- •To assess whether pre-operative maximum clot firmness value of the ROTEM graph can predict incidence of massive transfusion in patients undergoing liver transplant surgeries.
排除标准
- •Patient refusal
- •Patients undergoing combined liver kidney transplants.
结局指标
主要结局
A deranged maximum clot firmness value will predict the incidence of massive blood transfusion in patients undergoing liver transplant surgery.
时间窗: Pre-operative day | Post-operative day 0 or day of surgery
次要结局
- 1. Association of deranged MCF value on ROTEM with early allograft dysfunction(2. Association of deranged MCF on ROTEM with incidence of AKI)
研究者
Dr Sharika Sriramanan
Dr Rela Institute and Medical Centre