Heart rate variability in obese adolescents in relation to insulin levels during OGTT. A pilot study

• Conditions: diabetes; Metabolic syndrome; 10018424

• Registration Number: NL-OMON31491
• Lead Sponsor: Vrije Universiteit Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 13 May 2024

Recruitment & Eligibility

• Status: Pending
• Sex: Not specified
• Target Recruitment: 15

Inclusion Criteria

Boys, Age 12-18 years, BMI>95th perc.

Exclusion Criteria

Congenital or acquired heart disease, neurological disabilities, diabetes mellitus, medication that may influence the autonomic nervous system and/or insulin resistance or secretion.

Study & Design

• Study Type: Observational non invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The main parameters in this study will be LF (ms2), HF (ms2), LF/HF ratio, TP<br /><br>(ms2) and SDNN (ms). These parameters give information about the state of the<br /><br>central nervous system. BMI (kg/m2), cortisol (nmol/l), melatonin (pgram/ml),<br /><br>glucose (mmol/L), insulin levels (pmol/L) and the duration of obesity (months)<br /><br>will be considered as possible regressors. </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Not applicable</p><br>