NCT00434395已完成1 期
A Randomized, Double-Blind, Placebo- and Moxifloxacin (Open-Label)-Controlled, 4-Period Crossover Study of the Effects of a Single Dose of MOA-728 Infused Intravenously on Cardiac Repolarization in Healthy Subjects
适应症
相关药物
试验速览
- 阶段
- 1 期
- 状态
- 已完成
- 试验地点
- 1
- 主要终点
- Cardiac repolarization will be assessed by the QTc interval in healthy subjects.
研究概览
简要总结
The purpose of the study is to assess the effects of MOA-728 on cardiac repolarization in healthy subjects.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Treatment
- 盲法
- Double
入排标准
- 年龄范围
- 18 Years 至 50 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Generally healthy subjects men or women aged 18-50
排除标准
- •Any significant clinically important disease
- •Family history of long QT syndrome and/or sudden cardiac death
- •Allergy to moxifloxacin or the quinolone class of antibiotics
结局指标
主要结局
Cardiac repolarization will be assessed by the QTc interval in healthy subjects.
次要结局
未报告次要终点
研究者
研究点 (1)
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