dexamethasone and ketamine nebulisation beforesurgery relive the sorethroat after surgery

Completed

• Conditions: Medical and Surgical,

• Registration Number: CTRI/2020/07/026342
• Lead Sponsor: BJ medical college and civil hospital

Brief Summary

This is a prospective randomized study to compare the effictiveness of preoperative nebulisation of ketamine and dexamethasone to attenuate severity and incidence  post operative sore throat in patients undergoing surgery under general anaesthesia .  Patients will be followed up for post operative sore throat  and graded accordingly  for a period of 24 hours post operatively .

there are two groups

Group K - patients receiving preoperative nebulisation with ketamine 1ml(50 mg) with 4 ml normal saline

Group D - patients receiving preoperative nebulisation with dexamethasone  8mg (2ml ) with 3 ml normal saline

the hypothesis of this study is that preoperative nebulisation of these drugs reduces the incidence and severity of post operative sore throat

Detailed Description

Not available

Study Timeline

• Study Start: 2020-07-15
• Study Completion: 2020-10-20
• Last Update Posted: 2020-12-26

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

Asa 1 and 2 Elective surgeries under general anaesthesia Endotracheal intubation under general anaesthesia Supine position.

Exclusion Criteria

Preoperative sore throat , upper respiratory tract infection , chronic obstructive pulmonary disease, bronchial asthama Mallampatti grade >2 Patients undergoing oral surgeries , head and neck surgeries Allergy to any one or both studying drugs Pregnancy and lactating mother Current use of cortico steroids Immuno compromised patients /long term use of immunosuppressants patients with risk factors for post operative aspiration >1 attempt of intubation.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Comparison of efficacy of attenuating severity and incidence of postoperative sorethroat due to preoperative nebulisation .	Duration of reduction in post operative sore throat due to preoperative nebulisation upto 24 hours post operative period .

Secondary Outcome Measures

Name	Time	Method
Effectiveness of either of the drugs in reducing post operative sorethroat and side effects if any.	24 hour post operative period .

Trial Locations

Locations (1)

BJ Medical college and civil hospital ,Ahmedabad; 🇮🇳 Ahmadabad, GUJARAT, India

BJ Medical college and civil hospital ,Ahmedabad

🇮🇳Ahmadabad, GUJARAT, India

Dr Navya R Thota

Principal investigator

9607724054

navya.r.thota@gmail.com