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Comparing 2 different ratios of ketamine and propofol on patient vitals while giving anesthesia in abdominal surgeries

Phase 2
Conditions
Health Condition 1: R00-R99- Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
Registration Number
CTRI/2024/05/067027
Lead Sponsor
CMS and GTB Hospital
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
ot Yet Recruiting
Sex
Not specified
Target Recruitment
0
Inclusion Criteria

1)Consenting patients aged 18-65 years posted for expolrative laparotomy under general anaesthesia

2)Hemodynamically stable patients

Exclusion Criteria

1)Patient with heart block on peri operative ECG

2)Patient with heart rate less than 50bpm

3)Hemodynamically unstable patient with mean arterial pressure less than 60mmHg

4)Patient on inotropes

5)Patient with signs and symptoms of raised intracranial tension

6)Patient with known allergy to any of the drug used

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
To assess and compare incidence of hypotension between groups A and BTimepoint: Baseline 0 minute
Secondary Outcome Measures
NameTimeMethod
1) HR, SBP, DBP immediately post induction, <br/ ><br>2) HR, SBP, DBP immediately post intubation, <br/ ><br>3) Consumption of norepinephrine till 1 hour post intubation, <br/ ><br>4) Intubating conditions during intubation <br/ ><br>5) HR and MAP at the end of 5 minutes, 10 minutes 15 minutes, 20 minutes, 30 minutes and 1 hour, <br/ ><br>Timepoint: 1)post induction <br/ ><br>2)at the time of intubation <br/ ><br>3)post intubation <br/ ><br>4)5,10,15,20,30,60 minutes post intubation.
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