跳至主要内容
临床试验/NCT03722056
NCT03722056已完成不适用

Gastrointestinal Stromal Tumor of Stomach: Feasibility of Laparoscopic Resection in Large Lesions and Its Long Term Outcomes- A Case Series

GEM Hospital & Research Center0 个研究点目标入组 42 人开始时间: 2005年1月最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
42
主要终点
rates of intraoperative tumour rupture

研究概览

简要总结

Gastric GISTs are rare neoplasms that require excision for cure. Although the feasibility of laparoscopic resection of gastric GIST less than 2cms has been established, the feasibility, safety and long-term efficacy of these techniques for larger lesions are unclear. Investigators hypothesized that laparoscopic resection of gastric GISTs even for larger lesions is feasible & results in low perioperative morbidity and an effective long-term control of the disease.

详细描述

Open surgical resection was the standard of treatment until two decades ago, but with advent laparoscopy and experienced gained over the years, the safety & feasibility of laparoscopic resections of gastric GISTs has been proven but for tumors less than 2 cm. However, with gain of experience and skill in laparoscopic surgery, many surgeons have reported a safety & feasibility excision of tumors greater than 5 cm. Our current study demonstrates the oncologic safety of the laparoscopic approach even with tumour size range up to 12cm, with efficacy and recurrence rates similar or superior to historical open surgical controls, however, it requires considerable expertise for safe manipulation of the tumour. All these resections were accomplished with minimal morbidity, no perioperative mortality, and short post-operative stay and comparable long term oncological outcomes.

研究设计

研究类型
Observational
观察模型
Case Only
时间视角
Retrospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Gastric GIST>2cm size

排除标准

  • Metastatic GIST, not fit for GA

结局指标

主要结局

rates of intraoperative tumour rupture

时间窗: intraoperative

Any instances of tumour rupture during surgery is noted.

次要结局

未报告次要终点

研究者

发起方
GEM Hospital & Research Center
申办方类型
Other
责任方
Principal Investigator
主要研究者

Bhushan Chittawadagi

principal investigator

GEM Hospital & Research Center

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