Rectal Washout in Transanal Total Mesorectal Excision and Presence of Intraluminal Malignant Cells
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 21
- 试验地点
- 1
- 主要终点
- Existence of intraluminal malignant cells in fluid samples from rectal washout
研究概览
简要总结
The study aims to assess the existence of intraluminal malignant cells and the appropriate fluid volume needed to perform rectal washout during transanal total mesorectal excision (taTME) for rectal cancer.
详细描述
Twenty patients undergoing taTME for rectal cancer is included. Following the closure of the rectal lumen by a purse string suture, rectal washout is performed with a total of 500 ml sterile water. Fluid samples are collected after every 100 ml by instilling 50 ml of saline after each washout. A sixth sample is collected from the presacral cavity. Each sample is cytologically examined by a pathologist and labelled either malignant or non-malignant.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Surgery at Slagelse Hospital for rectal cancer with transanal mesorectal excision
- •Consent to participate in the study
排除标准
- •No consent to participate
- •No surgery
结局指标
主要结局
Existence of intraluminal malignant cells in fluid samples from rectal washout
时间窗: Intraoperatively
Positive/negative cytology
次要结局
- Fluid volume needed to perform rectal washout during transanal total mesorectal excision to eliminate intraluminal malignant cells(Intraoperatively)