Rectal Washout in Transanal Total Mesorectal Excision and Presence of Intraluminal Malignant Cells
- Conditions
- Rectal Cancer
- Interventions
- Procedure: Rectal washout
- Registration Number
- NCT04730102
- Lead Sponsor
- Slagelse Hospital
- Brief Summary
The study aims to assess the existence of intraluminal malignant cells and the appropriate fluid volume needed to perform rectal washout during transanal total mesorectal excision (taTME) for rectal cancer.
- Detailed Description
Twenty patients undergoing taTME for rectal cancer is included. Following the closure of the rectal lumen by a purse string suture, rectal washout is performed with a total of 500 ml sterile water. Fluid samples are collected after every 100 ml by instilling 50 ml of saline after each washout. A sixth sample is collected from the presacral cavity. Each sample is cytologically examined by a pathologist and labelled either malignant or non-malignant.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 21
- Surgery at Slagelse Hospital for rectal cancer with transanal mesorectal excision
- Consent to participate in the study
- No consent to participate
- No surgery
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description Patients undergoing rectal washout in transanal mesorectal excision Rectal washout Patients undergoing rectal washout in transanal mesorectal excision for rectal cancer.
- Primary Outcome Measures
Name Time Method Existence of intraluminal malignant cells in fluid samples from rectal washout Intraoperatively Positive/negative cytology
- Secondary Outcome Measures
Name Time Method Fluid volume needed to perform rectal washout during transanal total mesorectal excision to eliminate intraluminal malignant cells Intraoperatively Positive/negative cytology
Trial Locations
- Locations (1)
Slagelse Hospital
🇩🇰Slagelse, Zealand, Denmark